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DCAF6 has not been detected as a mutational cancer driver

DCAF6
Ensembl id ENSG00000143164
Mutated samples
Coding Sequence 63 (0.9%)
Protein Affecting 43 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all DCAF6 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 17 10 2.71
Lung adenocarcinoma No 8 6 1.53
Head and neck squamous cell carcinoma No 8 6 1.60
Breast carcinoma No 6 5 0.44
Uterine corpus endometrioid carcinoma No 5 5 2.17
Bladder carcinoma No 6 4 4.08
Acute myeloid leukemia No 1 1 0.51
Lung squamous cell carcinoma No 1 1 0.57
Serous ovarian adenocarcinoma No 1 1 0.32
Stomach adenocarcinoma No 1 1 0.62
Small cell lung carcinoma No 1 1 1.45
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 3 1 0.68
Prostate adenocarcinoma No 1 0 0.00
Renal clear cell carcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence