IntOGen - DCAF12L2 gene cancer mutations

DCAF12L2 is detected as a mutational cancer driver

DCAF12L2 reports

Methods
Mutation distribution

Gene details

DCAF12L2
Ensembl ID ENSG00000198354 Transcript ID ENST00000360028 Protein ID ENSP00000353128
Cancer types where is driver 3 Cohorts where is driver 3 Mutated samples 22 Mutations 554
Mode of action Activating
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence