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DBT has not been detected as a mutational cancer driver

DBT
Ensembl id ENSG00000137992
Mutated samples
Coding Sequence 26 (0.4%)
Protein Affecting 16 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all DBT gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 6 4 1.02
Head and neck squamous cell carcinoma No 3 3 0.80
Cutaneous melanoma No 4 2 0.54
Bladder carcinoma No 1 1 1.02
Breast carcinoma No 1 1 0.09
Pancreas adenocarcinoma No 1 1 0.47
Thyroid carcinoma No 1 1 0.31
Lower grade glioma No 1 1 0.59
Stomach adenocarcinoma No 1 1 0.62
Glioblastoma multiforme No 1 1 0.26
Hepatocarcinoma No 1 0 0.00
Lung squamous cell carcinoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence