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CYP1B1 has not been detected as a mutational cancer driver

CYP1B1
Ensembl id ENSG00000138061
Mutated samples
Coding Sequence 23 (0.3%)
Protein Affecting 15 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CYP1B1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 3 3 0.26
Cutaneous melanoma No 6 3 0.81
Lung adenocarcinoma No 2 2 0.51
Bladder carcinoma No 2 2 2.04
Stomach adenocarcinoma No 3 2 1.24
Serous ovarian adenocarcinoma No 1 1 0.32
Head and neck squamous cell carcinoma No 3 1 0.27
Glioblastoma multiforme No 1 1 0.26
Non small cell lung carcinoma No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence