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CTNNA2 has not been detected as a mutational cancer driver

CTNNA2
Ensembl id ENSG00000066032
Mutated samples
Coding Sequence 329 (4.8%)
Protein Affecting 151 (2.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CTNNA2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 53 25 6.78
Lung squamous cell carcinoma No 42 23 13.22
Lung adenocarcinoma No 35 22 5.63
Head and neck squamous cell carcinoma No 42 19 5.07
Esophageal carcinoma No 17 10 6.85
Stomach adenocarcinoma No 15 9 5.59
Breast carcinoma No 16 7 0.61
Pancreas adenocarcinoma No 4 4 1.87
Renal clear cell carcinoma No 8 4 0.96
Uterine corpus endometrioid carcinoma No 10 4 1.74
Small cell lung carcinoma No 8 4 5.80
Glioblastoma multiforme No 5 4 1.06
Prostate adenocarcinoma No 6 3 1.23
Bladder carcinoma No 9 3 3.06
Colorectal adenocarcinoma No 6 3 1.31
Hepatocarcinoma No 11 1 1.11
Acute myeloid leukemia No 1 1 0.51
Chronic lymphocytic leukemia No 25 1 0.34
Multiple myeloma No 2 1 1.45
Lower grade glioma No 1 1 0.59
Diffuse B cell lymphoma No 2 1 4.35
Acute lymphocytic leukemia No 1 1 0.82
Medulloblastoma No 3 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Serous ovarian adenocarcinoma No 3 0 0.00
Pylocytic astrocytoma No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence