IntOGen - CTNNA2 gene cancer mutations

CTNNA2 is detected as a mutational cancer driver

CTNNA2 reports

Methods
Mutation distribution

Gene details

CTNNA2
Ensembl ID ENSG00000066032 Transcript ID ENST00000402739 Protein ID ENSP00000384638
Cancer types where is driver 9 Cohorts where is driver 14 Mutated samples 107 Mutations 1,248
Mode of action Ambiguous
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence