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CSDE1 mutations in 6 cancer types possibly contribute to the detection of the gene in the PAN-cancer anlaysis:: Bladder carcinoma, Breast carcinoma, Lung squamous cell carcinoma, Serous ovarian adenocarcinoma, Stomach adenocarcinoma, Glioblastoma multiforme

CSDE1
Ensembl id ENSG00000009307
Mutated samples
Coding Sequence 264 (3.9%)
Protein Affecting 52 (0.8%)
Mode of action Loss of function
Known driver No
Cancer type Signals (Biases)
PAN
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CSDE1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma Yes 9 6 0.52
Stomach adenocarcinoma Yes 4 3 1.86
Bladder carcinoma Yes 4 2 2.04
Lung squamous cell carcinoma Yes 3 2 1.15
Serous ovarian adenocarcinoma Yes 4 2 0.63
Glioblastoma multiforme Yes 3 2 0.53
Uterine corpus endometrioid carcinoma No 16 10 4.35
Cutaneous melanoma No 107 8 2.17
Lung adenocarcinoma No 14 6 1.53
Head and neck squamous cell carcinoma No 6 5 1.33
Prostate adenocarcinoma No 1 1 0.41
Pancreas adenocarcinoma No 1 1 0.47
Renal clear cell carcinoma No 2 1 0.24
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 18 1 0.44
Esophageal carcinoma No 2 1 0.68
Hepatocarcinoma No 1 0 0.00
Acute myeloid leukemia No 15 0 0.00
Medulloblastoma No 1 0 0.00
Thyroid carcinoma No 26 0 0.00
Neuroblastoma No 2 0 0.00
Chronic lymphocytic leukemia No 4 0 0.00
Multiple myeloma No 16 0 0.00
Lower grade glioma No 1 0 0.00
Acute lymphocytic leukemia No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence