CREBBP mutations in 1 Neuroblastoma project possibly contribute to the detection of the gene in the PAN-cancer anlaysis:

Projects 1
210 Samples
Coding sequence mutations (CSMs)
in driver genes 92
in all genes 7150
Protein affecting mutations (PAMs)
in driver genes 87
in all genes 3973
Ensembl id ENSG00000005339
Mutated samples
Coding Sequence 2 (1.0%)
Protein Affecting 2 (1.0%)
Mode of action Loss of function
Known driver Yes
Project Signals
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated Neuroblastoma projects in all CREBBP gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Project Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Neuroblastoma Broad obtained from AlexandrovEtAl Yes 2 2 0.95
The mutations needle plot shows the distribution of the observed CREBBP cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence Driver classification