Top
CR1L has not been detected as a mutational cancer driver

CR1L
Ensembl id ENSG00000197721
Mutated samples
Coding Sequence 63 (0.9%)
Protein Affecting 47 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CR1L gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 28 19 5.15
Lung adenocarcinoma No 10 8 2.05
Stomach adenocarcinoma No 5 5 3.11
Head and neck squamous cell carcinoma No 3 3 0.80
Prostate adenocarcinoma No 3 2 0.82
Uterine corpus endometrioid carcinoma No 3 2 0.87
Bladder carcinoma No 1 1 1.02
Lung squamous cell carcinoma No 1 1 0.57
Neuroblastoma No 1 1 0.48
Chronic lymphocytic leukemia No 2 1 0.34
Multiple myeloma No 1 1 1.45
Lower grade glioma No 1 1 0.59
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 1 1 0.68
Hepatocarcinoma No 1 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence