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CR1 has not been detected as a mutational cancer driver

CR1
Ensembl id ENSG00000203710
Mutated samples
Coding Sequence 160 (2.4%)
Protein Affecting 127 (1.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CR1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 64 49 13.28
Lung adenocarcinoma No 15 13 3.32
Breast carcinoma No 14 11 0.96
Stomach adenocarcinoma No 10 9 5.59
Renal clear cell carcinoma No 7 7 1.68
Head and neck squamous cell carcinoma No 10 7 1.87
Lung squamous cell carcinoma No 9 6 3.45
Bladder carcinoma No 4 4 4.08
Uterine corpus endometrioid carcinoma No 5 4 1.74
Small cell lung carcinoma No 3 3 4.35
Colorectal adenocarcinoma No 3 3 1.31
Multiple myeloma No 3 2 2.90
Lower grade glioma No 2 2 1.18
Serous ovarian adenocarcinoma No 3 2 0.63
Esophageal carcinoma No 2 2 1.37
Prostate adenocarcinoma No 3 1 0.41
Acute myeloid leukemia No 1 1 0.51
Chronic lymphocytic leukemia No 1 1 0.34
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence