Top
CPSF3 has not been detected as a mutational cancer driver

CPSF3
Ensembl id ENSG00000119203
Mutated samples
Coding Sequence 45 (0.7%)
Protein Affecting 32 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CPSF3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 12 8 2.17
Breast carcinoma No 7 7 0.61
Lung adenocarcinoma No 2 2 0.51
Bladder carcinoma No 2 2 2.04
Lung squamous cell carcinoma No 4 2 1.15
Renal clear cell carcinoma No 2 2 0.48
Stomach adenocarcinoma No 4 2 1.24
Hepatocarcinoma No 2 1 1.11
Thyroid carcinoma No 1 1 0.31
Uterine corpus endometrioid carcinoma No 1 1 0.43
Non small cell lung carcinoma No 1 1 3.23
Small cell lung carcinoma No 2 1 1.45
Head and neck squamous cell carcinoma No 2 1 0.27
Esophageal carcinoma No 1 1 0.68
Prostate adenocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence