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CPS1 has not been detected as a mutational cancer driver

CPS1
Ensembl id ENSG00000021826
Mutated samples
Coding Sequence 193 (2.8%)
Protein Affecting 150 (2.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CPS1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 34 30 7.67
Cutaneous melanoma No 35 25 6.78
Lung squamous cell carcinoma No 23 22 12.64
Head and neck squamous cell carcinoma No 15 11 2.93
Stomach adenocarcinoma No 11 10 6.21
Breast carcinoma No 10 9 0.78
Glioblastoma multiforme No 8 7 1.85
Small cell lung carcinoma No 7 6 8.70
Renal clear cell carcinoma No 6 5 1.20
Bladder carcinoma No 5 4 4.08
Serous ovarian adenocarcinoma No 8 4 1.27
Esophageal carcinoma No 5 4 2.74
Uterine corpus endometrioid carcinoma No 4 3 1.30
Lower grade glioma No 4 3 1.78
Neuroblastoma No 2 2 0.95
Non small cell lung carcinoma No 2 2 6.45
Thyroid carcinoma No 1 1 0.31
Multiple myeloma No 1 1 1.45
Colorectal adenocarcinoma No 1 1 0.44
Prostate adenocarcinoma No 5 0 0.00
Hepatocarcinoma No 1 0 0.00
Medulloblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 3 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence