Top
COBLL1 has not been detected as a mutational cancer driver

COBLL1
Ensembl id ENSG00000082438
Mutated samples
Coding Sequence 86 (1.3%)
Protein Affecting 66 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all COBLL1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 28 18 4.88
Stomach adenocarcinoma No 9 6 3.73
Renal clear cell carcinoma No 5 5 1.20
Head and neck squamous cell carcinoma No 6 5 1.33
Lung adenocarcinoma No 4 4 1.02
Breast carcinoma No 5 3 0.26
Lower grade glioma No 3 3 1.78
Serous ovarian adenocarcinoma No 3 3 0.95
Small cell lung carcinoma No 3 3 4.35
Glioblastoma multiforme No 3 3 0.79
Bladder carcinoma No 2 2 2.04
Lung squamous cell carcinoma No 3 2 1.15
Uterine corpus endometrioid carcinoma No 2 2 0.87
Colorectal adenocarcinoma No 2 2 0.87
Esophageal carcinoma No 3 2 1.37
Hepatocarcinoma No 2 1 1.11
Pancreas adenocarcinoma No 1 1 0.47
Multiple myeloma No 1 1 1.45
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence