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CNTNAP5 has not been detected as a mutational cancer driver

CNTNAP5
Ensembl id ENSG00000155052
Mutated samples
Coding Sequence 278 (4.1%)
Protein Affecting 197 (2.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CNTNAP5 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 62 50 13.55
Lung adenocarcinoma No 40 32 8.18
Lung squamous cell carcinoma No 34 26 14.94
Head and neck squamous cell carcinoma No 18 16 4.27
Uterine corpus endometrioid carcinoma No 15 13 5.65
Esophageal carcinoma No 13 11 7.53
Breast carcinoma No 14 9 0.78
Stomach adenocarcinoma No 11 9 5.59
Serous ovarian adenocarcinoma No 10 6 1.90
Glioblastoma multiforme No 9 6 1.58
Prostate adenocarcinoma No 5 5 2.06
Small cell lung carcinoma No 5 5 7.25
Bladder carcinoma No 4 2 2.04
Multiple myeloma No 2 2 2.90
Acute myeloid leukemia No 1 1 0.51
Renal clear cell carcinoma No 1 1 0.24
Neuroblastoma No 2 1 0.48
Colorectal adenocarcinoma No 3 1 0.44
Acute lymphocytic leukemia No 1 1 0.82
Hepatocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 23 0 0.00
Pylocytic astrocytoma No 4 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence