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CNTN4 has not been detected as a mutational cancer driver

CNTN4
Ensembl id ENSG00000144619
Mutated samples
Coding Sequence 193 (2.8%)
Protein Affecting 123 (1.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CNTN4 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 71 56 15.18
Lung adenocarcinoma No 16 11 2.81
Stomach adenocarcinoma No 15 9 5.59
Head and neck squamous cell carcinoma No 11 8 2.13
Breast carcinoma No 8 7 0.61
Uterine corpus endometrioid carcinoma No 7 5 2.17
Lung squamous cell carcinoma No 7 4 2.30
Colorectal adenocarcinoma No 4 4 1.75
Glioblastoma multiforme No 5 4 1.06
Esophageal carcinoma No 6 3 2.05
Serous ovarian adenocarcinoma No 2 2 0.63
Prostate adenocarcinoma No 1 1 0.41
Hepatocarcinoma No 6 1 1.11
Bladder carcinoma No 1 1 1.02
Pancreas adenocarcinoma No 2 1 0.47
Neuroblastoma No 1 1 0.48
Non small cell lung carcinoma No 5 1 3.23
Chronic lymphocytic leukemia No 16 1 0.34
Multiple myeloma No 1 1 1.45
Lower grade glioma No 1 1 0.59
Small cell lung carcinoma No 1 1 1.45
Medulloblastoma No 1 0 0.00
Pylocytic astrocytoma No 4 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence