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CLASP2 mutations in 8 cancer types possibly contribute to the detection of the gene in the PAN-cancer anlaysis:: Lung adenocarcinoma, Bladder carcinoma, Breast carcinoma, Lung squamous cell carcinoma, Cutaneous melanoma, Serous ovarian adenocarcinoma, Stomach adenocarcinoma, Head and neck squamous cell carcinoma

CLASP2
Ensembl id ENSG00000163539
Mutated samples
Coding Sequence 71 (1.0%)
Protein Affecting 55 (0.8%)
Mode of action Loss of function
Known driver No
Cancer type Signals (Biases)
PAN
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CLASP2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma Yes 15 11 2.98
Lung adenocarcinoma Yes 7 5 1.28
Lung squamous cell carcinoma Yes 5 5 2.87
Breast carcinoma Yes 4 4 0.35
Bladder carcinoma Yes 3 3 3.06
Stomach adenocarcinoma Yes 4 3 1.86
Serous ovarian adenocarcinoma Yes 3 2 0.63
Head and neck squamous cell carcinoma Yes 3 2 0.53
Uterine corpus endometrioid carcinoma No 8 6 2.61
Prostate adenocarcinoma No 5 5 2.06
Glioblastoma multiforme No 2 2 0.53
Renal clear cell carcinoma No 2 1 0.24
Neuroblastoma No 1 1 0.48
Chronic lymphocytic leukemia No 2 1 0.34
Multiple myeloma No 1 1 1.45
Lower grade glioma No 1 1 0.59
Small cell lung carcinoma No 1 1 1.45
Esophageal carcinoma No 1 1 0.68
Colorectal adenocarcinoma No 1 0 0.00
Diffuse B cell lymphoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence