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CGN has not been detected as a mutational cancer driver

CGN
Ensembl id ENSG00000143375
Mutated samples
Coding Sequence 79 (1.2%)
Protein Affecting 53 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CGN gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 22 15 4.07
Lung adenocarcinoma No 7 5 1.28
Uterine corpus endometrioid carcinoma No 8 5 2.17
Breast carcinoma No 5 3 0.26
Medulloblastoma No 3 3 1.43
Lung squamous cell carcinoma No 4 3 1.72
Thyroid carcinoma No 3 3 0.93
Head and neck squamous cell carcinoma No 4 3 0.80
Serous ovarian adenocarcinoma No 3 2 0.63
Stomach adenocarcinoma No 2 2 1.24
Prostate adenocarcinoma No 1 1 0.41
Hepatocarcinoma No 2 1 1.11
Bladder carcinoma No 3 1 1.02
Acute myeloid leukemia No 1 1 0.51
Pancreas adenocarcinoma No 1 1 0.47
Renal clear cell carcinoma No 3 1 0.24
Small cell lung carcinoma No 1 1 1.45
Glioblastoma multiforme No 2 1 0.26
Acute lymphocytic leukemia No 1 1 0.82
Chronic lymphocytic leukemia No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence