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CFI has not been detected as a mutational cancer driver

CFI
Ensembl id ENSG00000205403
Mutated samples
Coding Sequence 62 (0.9%)
Protein Affecting 43 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CFI gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 31 22 5.96
Lung adenocarcinoma No 5 5 1.28
Head and neck squamous cell carcinoma No 6 5 1.33
Lung squamous cell carcinoma No 3 3 1.72
Stomach adenocarcinoma No 6 3 1.86
Breast carcinoma No 1 1 0.09
Neuroblastoma No 2 1 0.48
Uterine corpus endometrioid carcinoma No 1 1 0.43
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 1 1 0.68
Chronic lymphocytic leukemia No 5 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence