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CFHR5 has not been detected as a mutational cancer driver

CFHR5
Ensembl id ENSG00000134389
Mutated samples
Coding Sequence 98 (1.4%)
Protein Affecting 79 (1.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CFHR5 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 38 34 9.21
Lung adenocarcinoma No 8 8 2.05
Lung squamous cell carcinoma No 10 7 4.02
Colorectal adenocarcinoma No 5 5 2.18
Head and neck squamous cell carcinoma No 6 5 1.33
Breast carcinoma No 8 4 0.35
Uterine corpus endometrioid carcinoma No 3 3 1.30
Stomach adenocarcinoma No 4 3 1.86
Glioblastoma multiforme No 3 3 0.79
Lower grade glioma No 2 2 1.18
Prostate adenocarcinoma No 2 1 0.41
Hepatocarcinoma No 1 1 1.11
Thyroid carcinoma No 1 1 0.31
Neuroblastoma No 1 1 0.48
Esophageal carcinoma No 2 1 0.68
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Multiple myeloma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence