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CEP135 has not been detected as a mutational cancer driver

CEP135
Ensembl id ENSG00000174799
Mutated samples
Coding Sequence 68 (1.0%)
Protein Affecting 55 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CEP135 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung squamous cell carcinoma No 12 9 5.17
Cutaneous melanoma No 10 8 2.17
Lung adenocarcinoma No 7 5 1.28
Breast carcinoma No 5 5 0.44
Stomach adenocarcinoma No 5 5 3.11
Head and neck squamous cell carcinoma No 7 4 1.07
Renal clear cell carcinoma No 3 3 0.72
Bladder carcinoma No 2 2 2.04
Uterine corpus endometrioid carcinoma No 2 2 0.87
Chronic lymphocytic leukemia No 2 2 0.69
Multiple myeloma No 2 2 2.90
Serous ovarian adenocarcinoma No 2 2 0.63
Small cell lung carcinoma No 2 2 2.90
Colorectal adenocarcinoma No 2 2 0.87
Glioblastoma multiforme No 2 2 0.53
Hepatocarcinoma No 1 0 0.00
Lower grade glioma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence