CDKN2A is detected as a mutational cancer driver in Head and Neck Squamous Cell Carcinoma
CDKN2A reports in Head and Neck Squamous Cell Carcinoma (HNSC)
Cancer type details
Head and Neck Squamous Cell Carcinoma |
---|
Cohorts
6
Samples 818 Mutations 2,112,343 Driver genes 80 |
Gene details
CDKN2A |
---|
Ensembl ID
ENSG00000147889
Transcript ID ENST00000498124 Protein ID ENSP00000418915 |
Cohorts where is driver
5
Mutated samples 119 Mutated samples (%) 14.55 Mutations 155 |
Mode of action Ambiguous |
Known driver True |
Method signals per Cohort
Cohort | Methods | Samples | Samples (%) |
---|
In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
HNSC (Head and Neck Squamous Cell Carcinoma) | 1494 | 270 | 18.07 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Samples (%) | Consequence | Driver | Driver score |
---|