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CDKN2A × Bladder Urothelial Carcinoma ×

CDKN2A is detected as a mutational cancer driver in Bladder Urothelial Carcinoma

CDKN2A reports in Bladder Urothelial Carcinoma (BLCA)

Cancer type details
Bladder Urothelial Carcinoma
Cohorts 8
Samples 905
Mutations 6,585,575
Driver genes 89
Gene details
CDKN2A
Ensembl ID ENSG00000147889
Transcript ID ENST00000498124
Protein ID ENSP00000418915
Cohorts where is driver 2
Mutated samples 28
Mutated samples (%) 3.09
Mutations 36
Mode of action Loss of function
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence