CDKN2A is detected as a mutational cancer driver
CDKN2A reports
Gene details
CDKN2A |
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Ensembl ID
ENSG00000147889
Transcript ID ENST00000498124 Protein ID ENSP00000418915 |
Cancer types where is driver
24
Cohorts where is driver 70 Mutated samples 843 Mutations 1,171 |
Mode of action Ambiguous |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
HNSC (Head and Neck Squamous Cell Carcinoma) | 1494 | 270 | 18.07 |
LUNG_CANCER (Lung) | 1494 | 231 | 15.46 |
LUSC (Lung Squamous Cell Carcinoma) | 1494 | 270 | 18.07 |
CM (Melanoma) | 1494 | 265 | 17.74 |
PAAD (Pancreatic Adenocarcinoma) | 1494 | 230 | 15.39 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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