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CDC42BPA has not been detected as a mutational cancer driver

CDC42BPA
Ensembl id ENSG00000143776
Mutated samples
Coding Sequence 98 (1.4%)
Protein Affecting 64 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CDC42BPA gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 16 13 3.32
Breast carcinoma No 16 13 1.13
Cutaneous melanoma No 11 8 2.17
Lung squamous cell carcinoma No 8 7 4.02
Bladder carcinoma No 9 6 6.12
Renal clear cell carcinoma No 6 3 0.72
Uterine corpus endometrioid carcinoma No 5 3 1.30
Head and neck squamous cell carcinoma No 5 3 0.80
Small cell lung carcinoma No 3 2 2.90
Hepatocarcinoma No 1 1 1.11
Pancreas adenocarcinoma No 1 1 0.47
Serous ovarian adenocarcinoma No 2 1 0.32
Stomach adenocarcinoma No 4 1 0.62
Colorectal adenocarcinoma No 3 1 0.44
Esophageal carcinoma No 2 1 0.68
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 3 0 0.00
Lower grade glioma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence