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CD5L has not been detected as a mutational cancer driver

CD5L
Ensembl id ENSG00000073754
Mutated samples
Coding Sequence 93 (1.4%)
Protein Affecting 70 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CD5L gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 23 14 3.79
Lung adenocarcinoma No 14 13 3.32
Lung squamous cell carcinoma No 9 8 4.60
Breast carcinoma No 10 7 0.61
Uterine corpus endometrioid carcinoma No 6 5 2.17
Head and neck squamous cell carcinoma No 5 5 1.33
Esophageal carcinoma No 5 5 3.42
Hepatocarcinoma No 3 3 3.33
Stomach adenocarcinoma No 5 3 1.86
Bladder carcinoma No 2 2 2.04
Colorectal adenocarcinoma No 5 2 0.87
Prostate adenocarcinoma No 1 1 0.41
Serous ovarian adenocarcinoma No 1 1 0.32
Small cell lung carcinoma No 1 1 1.45
Glioblastoma multiforme No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence