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CD1C has not been detected as a mutational cancer driver

CD1C
Ensembl id ENSG00000158481
Mutated samples
Coding Sequence 82 (1.2%)
Protein Affecting 60 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CD1C gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 35 24 6.50
Lung adenocarcinoma No 8 7 1.79
Uterine corpus endometrioid carcinoma No 5 4 1.74
Breast carcinoma No 3 3 0.26
Lung squamous cell carcinoma No 5 3 1.72
Small cell lung carcinoma No 3 3 4.35
Head and neck squamous cell carcinoma No 3 3 0.80
Bladder carcinoma No 2 2 2.04
Neuroblastoma No 2 2 0.95
Serous ovarian adenocarcinoma No 2 2 0.63
Stomach adenocarcinoma No 4 2 1.24
Esophageal carcinoma No 3 2 1.37
Prostate adenocarcinoma No 1 1 0.41
Chronic lymphocytic leukemia No 1 1 0.34
Colorectal adenocarcinoma No 1 1 0.44
Hepatocarcinoma No 1 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence