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CCDC88A has not been detected as a mutational cancer driver

CCDC88A
Ensembl id ENSG00000115355
Mutated samples
Coding Sequence 97 (1.4%)
Protein Affecting 81 (1.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CCDC88A gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 16 12 3.25
Head and neck squamous cell carcinoma No 9 9 2.40
Lung adenocarcinoma No 10 8 2.05
Lung squamous cell carcinoma No 7 7 4.02
Stomach adenocarcinoma No 9 7 4.35
Breast carcinoma No 6 6 0.52
Bladder carcinoma No 6 5 5.10
Colorectal adenocarcinoma No 5 4 1.75
Uterine corpus endometrioid carcinoma No 5 3 1.30
Serous ovarian adenocarcinoma No 3 3 0.95
Renal clear cell carcinoma No 2 2 0.48
Small cell lung carcinoma No 2 2 2.90
Glioblastoma multiforme No 2 2 0.53
Esophageal carcinoma No 2 2 1.37
Prostate adenocarcinoma No 1 1 0.41
Hepatocarcinoma No 3 1 1.11
Medulloblastoma No 2 1 0.48
Pancreas adenocarcinoma No 1 1 0.47
Thyroid carcinoma No 1 1 0.31
Neuroblastoma No 1 1 0.48
Non small cell lung carcinoma No 1 1 3.23
Multiple myeloma No 1 1 1.45
Lower grade glioma No 1 1 0.59
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence