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CCDC158 has not been detected as a mutational cancer driver

CCDC158
Ensembl id ENSG00000163749
Mutated samples
Coding Sequence 103 (1.5%)
Protein Affecting 61 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CCDC158 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 32 18 4.88
Lung adenocarcinoma No 10 6 1.53
Small cell lung carcinoma No 5 5 7.25
Head and neck squamous cell carcinoma No 6 5 1.33
Glioblastoma multiforme No 6 5 1.32
Lung squamous cell carcinoma No 5 4 2.30
Stomach adenocarcinoma No 5 4 2.48
Breast carcinoma No 3 3 0.26
Serous ovarian adenocarcinoma No 4 3 0.95
Uterine corpus endometrioid carcinoma No 4 2 0.87
Hepatocarcinoma No 4 1 1.11
Renal clear cell carcinoma No 1 1 0.24
Neuroblastoma No 1 1 0.48
Lower grade glioma No 3 1 0.59
Colorectal adenocarcinoma No 4 1 0.44
Esophageal carcinoma No 2 1 0.68
Bladder carcinoma No 2 0 0.00
Non small cell lung carcinoma No 2 0 0.00
Pylocytic astrocytoma No 3 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence