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CCDC138 has not been detected as a mutational cancer driver

CCDC138
Ensembl id ENSG00000163006
Mutated samples
Coding Sequence 51 (0.8%)
Protein Affecting 30 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CCDC138 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Stomach adenocarcinoma No 8 5 3.11
Breast carcinoma No 4 4 0.35
Cutaneous melanoma No 11 4 1.08
Head and neck squamous cell carcinoma No 6 4 1.07
Lung adenocarcinoma No 3 2 0.51
Lung squamous cell carcinoma No 3 2 1.15
Uterine corpus endometrioid carcinoma No 3 2 0.87
Colorectal adenocarcinoma No 2 2 0.87
Esophageal carcinoma No 3 2 1.37
Bladder carcinoma No 3 1 1.02
Serous ovarian adenocarcinoma No 1 1 0.32
Glioblastoma multiforme No 1 1 0.26
Hepatocarcinoma No 1 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence