IntOGen - CASZ1 gene cancer mutations

CASZ1 is detected as a mutational cancer driver

CASZ1 reports

Methods
Mutation distribution

Gene details

CASZ1
Ensembl ID ENSG00000130940 Transcript ID ENST00000377022 Protein ID ENSP00000366221
Cancer types where is driver 1 Cohorts where is driver 1 Mutated samples 12 Mutations 688
Mode of action Loss of function
Known driver False

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence