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CASP8 has not been detected as a mutational cancer driver in this cancer type

Uterine corpus endometrioid carcinoma
Projects 1
230 Samples
Coding sequence mutations (CSMs)
in driver genes 1784
in all genes 68806
Protein affecting mutations (PAMs)
in driver genes 1591
in all genes 34136
CASP8
Ensembl id ENSG00000064012
Mutated samples
Coding Sequence 6 (2.6%)
Protein Affecting 4 (1.7%)
Mode of action Loss of function
Known driver No
Project Signals
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated Uterine corpus endometrioid carcinoma projects in all CASP8 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Project Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Uterine corpus endometrioid carcinoma TCGA No 6 4 1.74
The mutations needle plot shows the distribution of the observed CASP8 cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence Driver classification