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CADPS has not been detected as a mutational cancer driver

CADPS
Ensembl id ENSG00000163618
Mutated samples
Coding Sequence 157 (2.3%)
Protein Affecting 118 (1.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CADPS gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 35 27 7.32
Lung adenocarcinoma No 15 13 3.32
Stomach adenocarcinoma No 13 11 6.83
Breast carcinoma No 9 8 0.70
Lung squamous cell carcinoma No 13 8 4.60
Uterine corpus endometrioid carcinoma No 9 8 3.48
Colorectal adenocarcinoma No 7 7 3.06
Head and neck squamous cell carcinoma No 6 6 1.60
Esophageal carcinoma No 6 6 4.11
Glioblastoma multiforme No 6 5 1.32
Bladder carcinoma No 5 4 4.08
Serous ovarian adenocarcinoma No 4 4 1.27
Prostate adenocarcinoma No 5 3 1.23
Renal clear cell carcinoma No 3 3 0.72
Acute myeloid leukemia No 3 2 1.02
Hepatocarcinoma No 4 1 1.11
Multiple myeloma No 1 1 1.45
Small cell lung carcinoma No 1 1 1.45
Chronic lymphocytic leukemia No 10 0 0.00
Pylocytic astrocytoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence