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CADM3 has not been detected as a mutational cancer driver

CADM3
Ensembl id ENSG00000162706
Mutated samples
Coding Sequence 135 (2.0%)
Protein Affecting 54 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CADM3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 51 24 6.50
Lung adenocarcinoma No 17 3 0.77
Breast carcinoma No 6 3 0.26
Lung squamous cell carcinoma No 10 3 1.72
Stomach adenocarcinoma No 6 3 1.86
Small cell lung carcinoma No 6 3 4.35
Serous ovarian adenocarcinoma No 3 2 0.63
Prostate adenocarcinoma No 1 1 0.41
Hepatocarcinoma No 3 1 1.11
Bladder carcinoma No 3 1 1.02
Acute myeloid leukemia No 1 1 0.51
Pancreas adenocarcinoma No 1 1 0.47
Renal clear cell carcinoma No 3 1 0.24
Uterine corpus endometrioid carcinoma No 5 1 0.43
Non small cell lung carcinoma No 1 1 3.23
Chronic lymphocytic leukemia No 1 1 0.34
Colorectal adenocarcinoma No 1 1 0.44
Head and neck squamous cell carcinoma No 8 1 0.27
Glioblastoma multiforme No 2 1 0.26
Esophageal carcinoma No 4 1 0.68
Diffuse B cell lymphoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence