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C2orf78 has not been detected as a mutational cancer driver

C2orf78
Ensembl id ENSG00000187833
Mutated samples
Coding Sequence 71 (1.0%)
Protein Affecting 52 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all C2orf78 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 28 21 5.69
Lung adenocarcinoma No 11 10 2.56
Lung squamous cell carcinoma No 9 6 3.45
Renal clear cell carcinoma No 4 4 0.96
Breast carcinoma No 3 3 0.26
Stomach adenocarcinoma No 4 3 1.86
Bladder carcinoma No 3 1 1.02
Thyroid carcinoma No 1 1 0.31
Serous ovarian adenocarcinoma No 2 1 0.32
Head and neck squamous cell carcinoma No 2 1 0.27
Glioblastoma multiforme No 3 1 0.26
Small cell lung carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence