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C2orf71 has not been detected as a mutational cancer driver

C2orf71
Ensembl id ENSG00000179270
Mutated samples
Coding Sequence 126 (1.9%)
Protein Affecting 78 (1.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all C2orf71 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 50 36 9.76
Breast carcinoma No 13 8 0.70
Lung adenocarcinoma No 8 7 1.79
Lung squamous cell carcinoma No 9 5 2.87
Stomach adenocarcinoma No 5 3 1.86
Renal clear cell carcinoma No 4 2 0.48
Lower grade glioma No 2 2 1.18
Colorectal adenocarcinoma No 3 2 0.87
Head and neck squamous cell carcinoma No 5 2 0.53
Esophageal carcinoma No 4 2 1.37
Prostate adenocarcinoma No 3 1 0.41
Bladder carcinoma No 2 1 1.02
Medulloblastoma No 1 1 0.48
Pancreas adenocarcinoma No 1 1 0.47
Neuroblastoma No 1 1 0.48
Uterine corpus endometrioid carcinoma No 4 1 0.43
Multiple myeloma No 2 1 1.45
Small cell lung carcinoma No 3 1 1.45
Glioblastoma multiforme No 2 1 0.26
Chronic lymphocytic leukemia No 1 0 0.00
Serous ovarian adenocarcinoma No 2 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence