C1orf74 has not been detected as a mutational cancer driver

Ensembl id ENSG00000162757
Mutated samples
Coding Sequence 49 (0.7%)
Protein Affecting 9 (0.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all C1orf74 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung squamous cell carcinoma No 5 3 1.72
Lung adenocarcinoma No 7 2 0.51
Cutaneous melanoma No 19 2 0.54
Renal clear cell carcinoma No 1 1 0.24
Chronic lymphocytic leukemia No 1 1 0.34
Hepatocarcinoma No 2 0 0.00
Breast carcinoma No 4 0 0.00
Medulloblastoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 2 0 0.00
Stomach adenocarcinoma No 2 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
Head and neck squamous cell carcinoma No 2 0 0.00
Glioblastoma multiforme No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence