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C1orf186 has not been detected as a mutational cancer driver

C1orf186
Ensembl id ENSG00000196533
Mutated samples
Coding Sequence 19 (0.3%)
Protein Affecting 15 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all C1orf186 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 6 5 1.36
Lung adenocarcinoma No 3 2 0.51
Uterine corpus endometrioid carcinoma No 2 2 0.87
Head and neck squamous cell carcinoma No 2 2 0.53
Breast carcinoma No 1 1 0.09
Lung squamous cell carcinoma No 1 1 0.57
Small cell lung carcinoma No 1 1 1.45
Esophageal carcinoma No 1 1 0.68
Hepatocarcinoma No 1 0 0.00
Neuroblastoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence