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C1orf168 has not been detected as a mutational cancer driver

C1orf168
Ensembl id ENSG00000187889
Mutated samples
Coding Sequence 108 (1.6%)
Protein Affecting 77 (1.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all C1orf168 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 60 49 13.28
Lung adenocarcinoma No 7 6 1.53
Head and neck squamous cell carcinoma No 9 4 1.07
Uterine corpus endometrioid carcinoma No 4 3 1.30
Breast carcinoma No 4 2 0.17
Lung squamous cell carcinoma No 3 2 1.15
Renal clear cell carcinoma No 2 2 0.48
Serous ovarian adenocarcinoma No 2 2 0.63
Small cell lung carcinoma No 2 2 2.90
Bladder carcinoma No 1 1 1.02
Acute myeloid leukemia No 1 1 0.51
Lower grade glioma No 2 1 0.59
Stomach adenocarcinoma No 3 1 0.62
Esophageal carcinoma No 3 1 0.68
Hepatocarcinoma No 1 0 0.00
Medulloblastoma No 1 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence