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BRCA2 is detected as a mutational cancer driver

BRCA2 reports

Gene details
BRCA2
Ensembl ID ENSG00000139618
Transcript ID ENST00000380152
Protein ID ENSP00000369497
Cancer types where is driver 11
Cohorts where is driver 18
Mutated samples 167
Mutations 1,018
Mode of action Ambiguous
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence