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BCAN has not been detected as a mutational cancer driver

BCAN
Ensembl id ENSG00000132692
Mutated samples
Coding Sequence 98 (1.4%)
Protein Affecting 68 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all BCAN gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 17 12 3.25
Uterine corpus endometrioid carcinoma No 10 10 4.35
Lung adenocarcinoma No 14 8 2.05
Lung squamous cell carcinoma No 9 7 4.02
Head and neck squamous cell carcinoma No 11 6 1.60
Stomach adenocarcinoma No 6 5 3.11
Breast carcinoma No 4 4 0.35
Renal clear cell carcinoma No 5 4 0.96
Serous ovarian adenocarcinoma No 3 3 0.95
Bladder carcinoma No 3 2 2.04
Neuroblastoma No 2 2 0.95
Colorectal adenocarcinoma No 4 2 0.87
Prostate adenocarcinoma No 1 1 0.41
Acute myeloid leukemia No 1 1 0.51
Small cell lung carcinoma No 3 1 1.45
Pancreas adenocarcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence