Top
BAZ2B is detected as a mutational cancer driver in 3 cancer types: Lung adenocarcinoma, Cutaneous melanoma, Uterine corpus endometrioid carcinoma and in the PAN-cancer analysis

BAZ2B
Ensembl id ENSG00000123636
Mutated samples
Coding Sequence 145 (2.1%)
Protein Affecting 117 (1.7%)
Mode of action Activating
Known driver No
Cancer type Signals (Biases)
LUAD F
CM F
UCEC F
PAN
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all BAZ2B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma Yes 34 27 7.32
Head and neck squamous cell carcinoma Yes 16 13 3.47
Uterine corpus endometrioid carcinoma Yes 11 11 4.78
Lung adenocarcinoma Yes 10 10 2.56
Serous ovarian adenocarcinoma Yes 3 2 0.63
Small cell lung carcinoma Yes 2 2 2.90
Stomach adenocarcinoma No 13 11 6.83
Lung squamous cell carcinoma No 12 9 5.17
Renal clear cell carcinoma No 10 9 2.16
Bladder carcinoma No 7 7 7.14
Breast carcinoma No 8 7 0.61
Esophageal carcinoma No 5 4 2.74
Prostate adenocarcinoma No 1 1 0.41
Hepatocarcinoma No 6 1 1.11
Chronic lymphocytic leukemia No 2 1 0.34
Glioblastoma multiforme No 1 1 0.26
Acute lymphocytic leukemia No 1 1 0.82
Thyroid carcinoma No 2 0 0.00
Non small cell lung carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence