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ATP6V0B has not been detected as a mutational cancer driver

ATP6V0B
Ensembl id ENSG00000117410
Mutated samples
Coding Sequence 65 (1.0%)
Protein Affecting 11 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ATP6V0B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 11 5 0.44
Lung adenocarcinoma No 4 1 0.26
Bladder carcinoma No 2 1 1.02
Renal clear cell carcinoma No 2 1 0.24
Uterine corpus endometrioid carcinoma No 2 1 0.43
Stomach adenocarcinoma No 7 1 0.62
Head and neck squamous cell carcinoma No 2 1 0.27
Prostate adenocarcinoma No 2 0 0.00
Hepatocarcinoma No 1 0 0.00
Lung squamous cell carcinoma No 6 0 0.00
Cutaneous melanoma No 15 0 0.00
Neuroblastoma No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
Small cell lung carcinoma No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
Glioblastoma multiforme No 2 0 0.00
Esophageal carcinoma No 5 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence