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ATG4B has not been detected as a mutational cancer driver

ATG4B
Ensembl id ENSG00000168397
Mutated samples
Coding Sequence 42 (0.6%)
Protein Affecting 13 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ATG4B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 16 6 1.63
Uterine corpus endometrioid carcinoma No 5 2 0.87
Lung adenocarcinoma No 4 1 0.26
Hepatocarcinoma No 1 1 1.11
Bladder carcinoma No 2 1 1.02
Breast carcinoma No 1 1 0.09
Glioblastoma multiforme No 4 1 0.26
Prostate adenocarcinoma No 1 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Thyroid carcinoma No 1 0 0.00
Stomach adenocarcinoma No 3 0 0.00
Head and neck squamous cell carcinoma No 2 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence