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ASXL1 is detected as a mutational cancer driver

ASXL1 reports

Gene details
ASXL1
Ensembl ID ENSG00000171456
Transcript ID ENST00000375687
Protein ID ENSP00000364839
Cancer types where is driver 10
Cohorts where is driver 13
Mutated samples 73
Mutations 613
Mode of action Loss of function
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence