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ARID4B is detected as a mutational cancer driver in 1 cancer type: Breast carcinoma

ARID4B
Ensembl id ENSG00000054267
Mutated samples
Coding Sequence 115 (1.7%)
Protein Affecting 67 (1.0%)
Mode of action Loss of function
Known driver No
Cancer type Signals (Biases)
BRCA F
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ARID4B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma Yes 16 11 0.96
Cutaneous melanoma No 19 10 2.71
Lung squamous cell carcinoma No 9 7 4.02
Head and neck squamous cell carcinoma No 14 7 1.87
Bladder carcinoma No 6 5 5.10
Uterine corpus endometrioid carcinoma No 7 5 2.17
Stomach adenocarcinoma No 4 3 1.86
Prostate adenocarcinoma No 4 2 0.82
Lung adenocarcinoma No 6 2 0.51
Renal clear cell carcinoma No 5 2 0.48
Chronic lymphocytic leukemia No 3 2 0.69
Serous ovarian adenocarcinoma No 3 2 0.63
Glioblastoma multiforme No 5 2 0.53
Esophageal carcinoma No 4 2 1.37
Hepatocarcinoma No 5 1 1.11
Acute myeloid leukemia No 1 1 0.51
Non small cell lung carcinoma No 1 1 3.23
Colorectal adenocarcinoma No 1 1 0.44
Diffuse B cell lymphoma No 2 1 4.35
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence