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ARHGAP31 has not been detected as a mutational cancer driver

ARHGAP31
Ensembl id ENSG00000031081
Mutated samples
Coding Sequence 116 (1.7%)
Protein Affecting 81 (1.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ARHGAP31 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 19 15 4.07
Breast carcinoma No 11 10 0.87
Lung adenocarcinoma No 13 9 2.30
Uterine corpus endometrioid carcinoma No 13 8 3.48
Head and neck squamous cell carcinoma No 9 8 2.13
Lung squamous cell carcinoma No 9 5 2.87
Renal clear cell carcinoma No 6 5 1.20
Stomach adenocarcinoma No 9 5 3.11
Bladder carcinoma No 4 3 3.06
Esophageal carcinoma No 4 3 2.05
Non small cell lung carcinoma No 2 2 6.45
Small cell lung carcinoma No 3 2 2.90
Prostate adenocarcinoma No 2 1 0.41
Hepatocarcinoma No 4 1 1.11
Pancreas adenocarcinoma No 1 1 0.47
Neuroblastoma No 1 1 0.48
Serous ovarian adenocarcinoma No 2 1 0.32
Colorectal adenocarcinoma No 2 1 0.44
Chronic lymphocytic leukemia No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence