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ARHGAP15 has not been detected as a mutational cancer driver

ARHGAP15
Ensembl id ENSG00000075884
Mutated samples
Coding Sequence 86 (1.3%)
Protein Affecting 52 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ARHGAP15 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 14 9 2.44
Lung adenocarcinoma No 7 6 1.53
Head and neck squamous cell carcinoma No 6 6 1.60
Colorectal adenocarcinoma No 6 5 2.18
Breast carcinoma No 5 4 0.35
Stomach adenocarcinoma No 4 4 2.48
Small cell lung carcinoma No 5 4 5.80
Esophageal carcinoma No 5 4 2.74
Hepatocarcinoma No 9 3 3.33
Bladder carcinoma No 2 2 2.04
Lung squamous cell carcinoma No 4 2 1.15
Non small cell lung carcinoma No 1 1 3.23
Serous ovarian adenocarcinoma No 1 1 0.32
Glioblastoma multiforme No 3 1 0.26
Medulloblastoma No 1 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 7 0 0.00
Pylocytic astrocytoma No 3 0 0.00
Diffuse B cell lymphoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence