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ARHGAP10 has not been detected as a mutational cancer driver

ARHGAP10
Ensembl id ENSG00000071205
Mutated samples
Coding Sequence 57 (0.8%)
Protein Affecting 38 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ARHGAP10 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 17 12 3.25
Uterine corpus endometrioid carcinoma No 5 4 1.74
Head and neck squamous cell carcinoma No 5 4 1.07
Lung adenocarcinoma No 4 3 0.77
Lung squamous cell carcinoma No 3 3 1.72
Hepatocarcinoma No 2 2 2.22
Renal clear cell carcinoma No 2 2 0.48
Prostate adenocarcinoma No 1 1 0.41
Bladder carcinoma No 1 1 1.02
Breast carcinoma No 2 1 0.09
Pancreas adenocarcinoma No 1 1 0.47
Multiple myeloma No 1 1 1.45
Small cell lung carcinoma No 2 1 1.45
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 2 1 0.68
Chronic lymphocytic leukemia No 4 0 0.00
Pylocytic astrocytoma No 2 0 0.00
Stomach adenocarcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence