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APOA2 has not been detected as a mutational cancer driver

APOA2
Ensembl id ENSG00000158874
Mutated samples
Coding Sequence 24 (0.4%)
Protein Affecting 5 (0.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all APOA2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 6 1 0.26
Lung squamous cell carcinoma No 2 1 0.57
Cutaneous melanoma No 3 1 0.27
Uterine corpus endometrioid carcinoma No 1 1 0.43
Head and neck squamous cell carcinoma No 1 1 0.27
Hepatocarcinoma No 2 0 0.00
Renal clear cell carcinoma No 2 0 0.00
Multiple myeloma No 1 0 0.00
Stomach adenocarcinoma No 1 0 0.00
Small cell lung carcinoma No 2 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
Glioblastoma multiforme No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence