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AP1AR has not been detected as a mutational cancer driver

AP1AR
Ensembl id ENSG00000138660
Mutated samples
Coding Sequence 11 (0.2%)
Protein Affecting 7 (0.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all AP1AR gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 2 2 0.17
Cutaneous melanoma No 1 1 0.27
Neuroblastoma No 1 1 0.48
Uterine corpus endometrioid carcinoma No 1 1 0.43
Stomach adenocarcinoma No 1 1 0.62
Colorectal adenocarcinoma No 1 1 0.44
Medulloblastoma No 1 0 0.00
Lung squamous cell carcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence