Top
AGBL5 has not been detected as a mutational cancer driver

AGBL5
Ensembl id ENSG00000084693
Mutated samples
Coding Sequence 79 (1.2%)
Protein Affecting 49 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all AGBL5 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 21 12 3.25
Head and neck squamous cell carcinoma No 8 7 1.87
Breast carcinoma No 7 5 0.44
Uterine corpus endometrioid carcinoma No 5 5 2.17
Stomach adenocarcinoma No 7 5 3.11
Lung adenocarcinoma No 7 4 1.02
Serous ovarian adenocarcinoma No 3 3 0.95
Lung squamous cell carcinoma No 4 2 1.15
Prostate adenocarcinoma No 2 1 0.41
Pancreas adenocarcinoma No 2 1 0.47
Neuroblastoma No 1 1 0.48
Lower grade glioma No 1 1 0.59
Colorectal adenocarcinoma No 3 1 0.44
Esophageal carcinoma No 4 1 0.68
Hepatocarcinoma No 1 0 0.00
Bladder carcinoma No 1 0 0.00
Multiple myeloma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence